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Your vaginal microbiome naturally fluctuates with your cycle, hormones, stress levels, and daily routines. But when that balance is disrupted, it can cause odor, discomfort, or a lingering sense that something’s just off. That’s why many women choose probiotics designed specifically for vaginal health.

To help you find the right one, we’ve reviewed the top vaginal probiotics of 2025—ranking them by ingredients, proven effectiveness, and real user experiences.

DISCLAIMER: This scientific research is for informational purposes only. The results reported may not necessarily occur in all individuals. Primal Harvest provides this information as a service but does not endorse it. This information should not be read to recommend or endorse any specific products.

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1. Integrative HMP (iHMP) Research Network Consortium. “The Integrative Human Microbiome Project: dynamic analysis of microbiome-host omics profiles….” Cell host & microbe vol. 16,3 (2014): 276-89. doi:10.1016/j.chom.2014.08.014

2. Sender, Ron et al. “Revised Estimates for the Number of Human and Bacteria Cells in the Body.” PLoS biology vol. 14,8 e1002533. 19 Aug. 2016, doi:10.1371/journal.pbio.1002533

3. Durack, Juliana, and Susan V Lynch. “The gut microbiome…” The Journal of experimental medicine vol. 216,1 (2019): 20-40. doi:10.1084/jem.20180448

4. Al Bander, Zahraa et al. “The Gut Microbiota…: An Overview.” International journal of environmental research and public health vol. 17,20 7618. 19 Oct. 2020, doi:10.3390/ijerph17207618

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To see a list of our other references, please click here. 

PROS

CONS

• Only available online
• Sometimes runs out of stock

BOTTOM LINE

A+

GRADE

• Contains 12 dynamic probiotic strains 
• With 31 billion CFUs
• With Red Raspberry Seed and FOS Prebiotics
• Made in the USA with globally sourced ingredients
• 90-day money-back guarantee
• Third-party lab tested
• Convenient once-daily capsule

Primal Probiotics by Primal Harvest delivers 31 billion CFUs from 12 diverse probiotic strains, plus Red Raspberry Seed and FOS prebiotics for enhanced support. The once-daily, delayed-release capsules are easy to take and help ensure the probiotics reach where they’re needed. It’s third-party tested, made in the USA, and was the only product on this list backed by a 90-day money-back guarantee. 

2. Happy Hoo-Ha

by OLLY

PROS

• Includes Lactobacillus acidophilus La-14 and Lactobacillus rhamnosus HN001
• No artificial additives

CONS

• No prebiotics
• Under 20 billion CFUs (10 billion per serving)

BOTTOM LINE

Happy Hoo-Ha by OLLY includes 2 Lactobacillus strains: Lactobacillus acidophilus La-14 and Lactobacillus rhamnosus HN001. It’s also free from artificial additives, gluten, and sugar. 

However, their ‘Vaginal Probiotic Blend’ contains just 10 billion CFUs of probiotics.  The formula also doesn’t include prebiotics, which could impact its overall efficacy.

B+

GRADE

3. Once Daily Women's

by Garden of Life

PROS

• Includes Lactobacillus and Bifidobacterium strains
• Organic prebiotic fiber blend

CONS

• No delayed-release capsules
• Shorter return window (60 days)

BOTTOM LINE

This probiotic features a blend of Lactobacillus and Bifidobacterium cultures, plus an organic prebiotic fiber blend for added support. It's a solid choice for women looking for a supplement with good probiotic diversity.

Unlike our top pick, it lacks delayed-release capsules, which may affect how many probiotics survive digestion and stomach acid to deliver effective results. The return policy is also limited to 60 days.

B

GRADE

by RenewLife

PROS

• Includes diverse Lactobacillus and Bifidobacterium strains
• Convenient once-daily capsule

CONS

• No prebiotics
• Shorter return window (60 days)

BOTTOM LINE

Women’s Care Probiotic by RenewLife includes a range of Lactobacillus and Bifidobacterium strains to support digestive and feminine health. The once-daily capsule makes it convenient to incorporate into a daily routine.

However, the formula doesn’t include any prebiotics for additional support, and once again, the money-back guarantee is limited to 60 days.

C+

GRADE

4. Women's Care Probiotic

5. URO Probiotic

by OPositiv

PROS

• Includes XOS prebiotics
• Lactobacillus probiotic blend

CONS

• Low CFU count (5 billion per serving)
• Single strain group (Bifidobacterium only)

BOTTOM LINE

URO Probiotic by OPositiv includes a Lactobacillus blend and XOS prebiotics, which can help nourish good bacteria. It’s a straightforward formula with a clean label and simple ingredient profile.

That said, it delivers just 5 billion CFUs and relies primarily on a single strain group - Bifidobacterium, which may limit its overall diversity and potential impact.

C

GRADE

Our Choice

• Supports vaginal microbiome and feminine wellness*
• 12 dynamic probiotic strains 
• 31 billion CFUs probiotics
• Includes prebiotics to help nourish good bacteria.*
• Made in the USA with globally sourced ingredients
• 90-day money-back guarantee

Learn More

Based on 3732 Reviews of Primal Harvest 

Is Your Vaginal Microbiome Out of Balance?

Even with the best hygiene and habits, your vaginal flora can shift. Here are some signs that your vaginal microbiome may be unbalanced.

• A lingering, unpleasant odor
• Unusual discharge
• Itching, dryness, or irritation
• Feeling ‘off’ around your cycle or after intimacy
• A general sense of unease or discomfort

Your vaginal microbiome is very senstive, and can be negatively influenced by factors such as:

• Hormonal fluctuations
• Stress
• Sexual activity 
• Antibiotics
• Lifestyle choices (such as smoking or douching)

Not all probiotics are created equal—here’s how to spot the good ones (and skip the rest):

Probiotic Checklist: What Matters—and What Doesn’t

How Probiotics Support Vaginal Health

A healthy vaginal microbiome depends on Lactobacillus bacteria to keep pH levels in check and protect against disruptive bacteria and yeast. But factors like stress, antibiotics, and hormonal shifts can throw that balance off—leading to discomfort or recurring issues. That’s where targeted probiotics come in.

Specific strains like Lactobacillus rhamnosus, acidophilus, reuteri, and gasseri are known for their ability to support vaginal health by maintaining optimal pH, strengthening your body’s natural defenses, and promoting lasting balance.

The best probiotic formulas don’t stop there—they also include prebiotics like FOS to fuel good bacteria and use delayed-release capsules that help the probiotics survive the digestive process and reach the areas where they’re needed most.

Everyone’s microbiome is unique, but probiotic supplements may be helpful for women who:

Is A Probiotic Right For You?

• Want consistent support for vaginal balance and comfort*
• Deal with consistent unpleasant vaginal odor.*

Note: These statements are not intended to diagnose, treat, cure, or prevent any disease or condition. They are based on personal experiences and subjective feedback. Always consult your healthcare provider for individual guidance.

• Experience occasional irritation, discharge, or imbalance*
• Are looking for a daily probiotic that supports both vaginal and digestive health*

• Multi-strain formulas (10+ strains)

More strains provide broader support for a balanced microbiome.

• High CFU counts of key strains (L. reuteri, L. gasseri, L. casei)

These strains are essential for maintaining vaginal pH balance and overall health.

• Lactobacillus and Bifidobacterium species

These strains help promote a healthy vaginal environment by supporting beneficial bacteria.

• Prebiotics like FOS

Prebiotics fuel probiotics, enhancing their effectiveness and survival.

• Delayed-release capsules

Protects probiotics from stomach acid, ensuring they reach the vaginal tract intact.

• Botanical ingredients (e.g., Red Raspberry Seed)

Natural plant-based ingredients can provide additional support for reproductive health.

• Clean, transparent labels

Look for products free from artificial additives, fillers, and allergens.

Though results vary, here’s what you might expect from consistent use of a high-quality probiotic over time:

• Smoother digestion and less bloating*
• Feeling fresher throughout the day*
• Fewer cravings for sugar or simple carbs*

How Can Probiotics Support Your Vaginal Health?

SHORT TERM

LONG TERM

• Ongoing support for vaginal and gut health*
• Feeling lighter, more comfortable, and more satisfied overall*

MID TERM

• Improved vaginal comfort*
• Clearer-looking skin*
• More regular digestion and elimination*

Note: Individual results may vary. These benefits are based on personal experiences and subjective feedback and may not apply to everyone.

What To Look For...

• Artificial additives, fillers, or sweeteners

These unnecessary ingredients may compromise the purity and effectiveness of the probiotic.

• Unclear or incomplete ingredient lists

Avoid products with vague or incomplete labels that don’t clearly show what’s inside.

• Single-strain formulas

Lack of strain diversity limits effectiveness and doesn’t support a well-rounded microbiome.

• Low CFU counts

Insufficient colony-forming units may not provide noticeable results or support long-term balance.

• Lack of prebiotics

Without prebiotics, probiotics may not survive long enough to offer full benefits.

Happy Hoo-Ha by OLLY

Once Daily Women’s by Garden Of Life

URO Probiotic by OPositiv

Good To Have

Important Criteria

*We try to update product information as often as we can. Please visit product websites for more information.

Try To Avoid

90-Day Money-Back Guarantee

Third-Party Tested

Subscribe & Save Program

Women’s Care Probiotic by RenewLife

Top Probiotics for Vaginal Health in 2025

20+ Billion CFUs

Lactobacillus Strains 

Bifidobacterium Strains 

Prebiotics

Delayed Release Capsules

Artificial Additives 

Low CFU counts (under 20 billion)

Single-Strain Formula